How Music Influences Memory Essay

I lay in my bed listening to the endless stream of music coming through my headphones. My iTunes is on shuffle, some songs I skip but most of them I let play without interference. Zoning out only enough to let my mind wonder, I relax and take in the sounds surrounding me. I feel restful, at piece. A brief moment of silence from the time one song ends and another begins. I hear the first five notes on a piano — instantly, I have a lump in my throat, my heart quickens, and my eyes begin to sting. â€Å"Through the Years† by Kenny Rogers has just come on. After fifteen seconds of a piano introduction, Rogers’ soothing voice starts in, â€Å"I can’t remember when you weren’t there†¦ I am reminded of my family. I am taken back to a time when all my grandparents were still alive and well. My father’s mother’s face comes into view, she has been gone twelve years but I can almost feel her presence. I think of the love my family and I have for each other. I think of my sister. My cheeks and ears begin to feel warm. The air I’m breathing suddenly becomes thick, my vision is blurred by the water filling my eyes. The chorus begins, â€Å"Through the years†¦Ã¢â‚¬  My eyes overflow and tears silently fall down my face. After the second chorus the song builds on itself, it rises and keeps on rising. The tension is broken by Rogers’ voice full of love and sincerity at the bridge. I have graduated from softly crying to full on sobbing. My face, my ears, my neck and my pillow are wet with tears. What I am crying about, I am not entirely certain of. What I am certain of, however, is that this wave of emotion that I am drowning in was induced solely by this song. Now in the fetal position, cuddling the blanket and bear that I have had since I was born, I gasp and choke a deep breath in and cough it out as I sob. â€Å"As long as it’s okay / I’ll stay with you / Through the years† The song ends, and after a short while I return to the restful state I was in prior to my breakdown, noticeably more tired. All of this because of a song. This experience and countless others like it (varying in memories and emotions) that made me wonder about the power of music. We have all been influenced by music at one point in our lives; oose bumps, shivers, hair standing on end, tears, dancing, tapping to the beat. Music is all around us, and it is there no matter where you go; it transcends borders and cultures, it is the one universal thing that does. Henry Wadsworth Longfellow said it best: â€Å"Music is the universal language of mankind. † Music has the ability to elicit emotions and trigger memories of our past, transporting us to a specific moment or time in our lives. Music can help us cope, the proof of this is in the success of break-up songs. We rely on music. But, what is it about music that makes it so powerful? How is it able to influence us the way it does? Studying music from a scientific approach is relatively new practice, especially music and its effects on the brain. Thanks to advances in neuroscience such a study is made possible. Neuroscientists use fMRI and PET scans to study the brain and what music does to it. When we listen to music different parts of our brain are stimulated. What scientists have learned is that music activates more areas of the brain than anything else. Elena Mannes, author of the book The Power of Music: Pioneering Discoveries in the New Science of Song, identifies some of parts and functions of the brain that are used to process music: †¦the auditory cortex (first stage in the listening process, perception and analysis of tones), the motor cortex (foot tapping, playing an instrument), the prefrontal cortex (the creation of expectations triggered by musical patterns and the violation of patterns/expectations), the sensory cortex (tactile feedback, as in playing an instrument), the visual cortex (reading music), the nucleus accumbens and the amygdala (emotional reactions), the hippocampus (memory for music), the cerebellum (also movement and emotional reactions). (Mannes, 32). When we listen to music our brain is actually extracting something from the music and making sense of it. Some scientists believe that this could contribute to our brain’s ability to remember songs so well. (Kunz). An intriguing aspect of music and how we relate to it is our seemingly instinctual ability to analyze a piece of music. Daniel Levitin, a neuroscientist at McGill University, discusses in his book, This Is Your Brain On Music: The Science of a Human Obsession, how our brain perceives and understands music. When we start out we have thousands of neurons in our brains that are completely free, not tied down or associated to anything. However, as we grow and learn, these neurons are shaped by experience and make connections. Through our experiences our brains learn the rules of whatever music we are exposed to. For example, we have songs that we recognize as happy or sad, even if it is only an instrumental piece. We are able to recognize the mood or feeling of a song from its elements; in Western society we tend to associate a fast tempo with energy and spiritedness and a slow tempo with sadness. These associations, or connections, are learned from our experiences. (Levitin, 87-89). There are a variety of different factors that contribute to our physical and emotional reactions to music. Music often mirrors the natural world and picks up on cues that are prevalent in human behavior. Expectations not fulfilled, surprise, when something happens not as planned, often in life these are what elicit our strongest emotions. Composers employ structural devices that imitate these real-life occurrences and thereby prompt a reaction from the listener. An easily relatable physical reaction to music is called frisson, or more commonly referred to as goose bumps or shivers down one’s spine. These reactions can and are most commonly achieved through the use of an enharmonic change. A simple example (in simple terms, the following chords and notes do not actually exist) of an enharmonic change is when chord(x) is played and harmonizes melody note(a), (this chord is often played again at least once, if not more) then chord(y) is played and re-harmonizes melody note(a), so it is the same but different. The composer creates an expectation and then those expectations are not carried out and that elicits a reaction from the listener (Mannes, 283). A myriad of elements contribute to the influencing power music has over our emotions. Two of the main reasons people listen to music is for emotional impact and regulation (Chanda and Levitin, 180). Music can provide us with a wide range of feelings, such as happiness, sadness, excitement and tranquility Music is also known to produce feelings of euphoria, and what some even describe as a high. Scientists have discovered the reason for this so-called high: the areas in the brain that are activated by drugs or during sex are also activated by listening to music that we enjoy. Listening to pleasurable music activates the production of neurochemicals. The most recognizable chemical that is produced is dopamine, the feel-good hormone, a neurotransmitter responsible for mood regulation. Prolactin, the comfort or satisfaction hormone, normally associated with mothers breastfeeding their infant, is also produced. The third chemical produced is oxytocin, the cuddle or trust hormone commonly associated with sex and bonding with other people. The production of these hormones explain the â€Å"euphoric† feeling people sometimes experience when listening to music. These hormones also influence our mood and perception (Chanda and Levitin180; Mannes, 35). Another factor that contributes to our emotional response to music is our emotional connection to a song. Often times, memories that we associate with a particular song that we heard in a particular time in our lives are triggered when we hear that song. Researchers have found that there is a significant difference in brain activity when we hear a song that we have emotional connections to. A potential and simple explanation for this is that we are not only processing the music but we are also recalling past events. Memories are stored as proteins in different parts of our brains, when memories are triggered, different parts of the brain are put into action to recall those memories. Both functions (processing music and remembering) use a large portion of our brain on their own, combine the two and that is a lot of brain activity (Kunz). Memories triggered by music are often times much more powerful than when triggered simply by thought. For example, a friend might say, â€Å"Do you remember when†¦Ã¢â‚¬  and we reminisce with our friend about a time or an event of past. We may laugh, or feel a sentimental twinge of longing, but usually, not more than that. When a memory is triggered by a song, however, we are somehow transported back in time and are able to experience the feelings we had at that time. There has been speculation for why our memories are much more vivid when triggered by music. Some have theorized that because our brain has already done the work of processing a particular piece of music, we recognize that we have done it before. The recognition of that precise action manifests itself through our feelings. For example, when I hear the song â€Å"Crazy† by Gnarls Barkley, I am immediately taken back to the summer of 2006. I am instantly overcome with a feeling that I can only describe as being the feeling I felt the summer I was sixteen. It’s a happy feeling; a feeling of freedom mixed with confusion and carelessness. My senses are activated; I am able to smell the salt air from the beach, I can taste the Arizona Raspberry Iced Tea that I perpetually consumed, I am almost able to feel my jean shorts around my legs, I even have a clear vision of Highway 33 from the passenger’s seat of mine and my sister’s car as we make our way to the beach, the scene before me shaded by the sunglasses I wore. When a memory is triggered by one of the senses, the other senses are triggered as well. Our senses dictate what we perceive, and therefore, influence how we feel. At that time in my life when my brain was processing that song, it was also processing all of my other senses, all of these elements combined and gave me a very specific feeling. So now when I hear that song, my brain processes it and says something like, Oh, I have done this before, this is the result. It can be likened to muscle memory (Kunz). Intrigued by the power music has, I interviewed Matthew J. Kunz, a researcher currently exploring potential methods to treat patients suffering from neurological injuries and illnesses. One medium of particular interest to him is forms of music therapy. It has been proven that music engages and even enhances motor and auditory skills. Music could potentially serve as a form of physical therapy after an injury or an illness that has impaired an individual’s motor skills. A great example of this is Parkinson’s disease. Humans are instinctively able to march or walk to a beat. By providing someone with a rhythm track their actions, e. g. walking, could be improved if accompanied by music (Kunz). Another neurological illness that is being treated by music is Alzheimer’s disease. However severe a dementia is, even if the patient has lost language, they almost never seem to lose the memory or ability to respond to music. Not only can it assist in the recalling of memories but it can also strengthen areas of the brain. Some music therapists have the patient learn and play music. Somehow, the ability to do this stays in their brain, once the song is in there (their brain) it stays. Through learning and playing music the patient exercises their brain, and as a result, functions of the brain, like motor skills, are improved. Even severely demented patients will recognize old songs and be delighted by them. Kunz confesses, â€Å"If nothing else, the patients are able to experience joy. Even if that’s the only thing it gave them, it would be worth the work that is being done now. † Kunz’s heart is in the right place regardless of the outcome of the research, however, studies have already shown the positive benefits of the diverse forms of musical therapy (Kunz). Whether we want to feel rapture and be delighted by something, or shed a few tears, if we are in need of therapy, or simply want to break the silence, music is there for us. The power music holds is so strong that we depend on it and integrate it to nearly every aspect of our lives. Ill, or injured, or completely well, music is therapeutic to us all; it can bring groups of people together or provide a sense of company when one is alone. It makes our highest highs higher and our lowest lows lower, but that is the magic and power of music. I am certain that our existence and experience as human beings would be far less than what it is if it were not for music.

The Theory And Practice Of Natural Managment Environmental Sciences Essay

In the latest Living Planet Report building and route edifice was noted as being one of the largest drivers of biodiversity loss due to human activities ( WWF, 2008 ) . As planetary concern about society ‘s impact on the environment rises, the force per unit area on administrations to work to a higher environmental criterion is increasing. With the of all time turning consciousness and significance of environmental impact the successful execution of an effectual Environmental Management System ( EMS ) is going more of import that of all time earlier. The principle for this thesis is that by successfully implementing an EMS administrations can better their environmental public presentation and hence aid cut down the negative effects human activity has on the environment. Integrating an EMS will non assist pull off the environment straight but alternatively dressed ores on put ining environmental ends into mundane processs with the purpose of cut downing an administrations negative impacts ( Sheldon, Yoxon, 2006, page 2 ) . Developing a civilization of attention through environmental preparation, consciousness and communicating may help administrations in bettering their environmental public presentation. BS EN ISO 14001 provides counsel for organisations â€Å" concerned with accomplishing and showing sound environmental public presentation † to develop systems to pull off their environmental duties. Developing an environmental policy without enfranchisement to criterions with the purpose of stand foring an EMS is possible ( Hyde and Reeve, 2006 ) . However, conformity to criterions provides a figure of benefits. For an administration to run into the demands of an ISO based EMS it must besides integrate â€Å" preparation, consciousness and competency † . As BS EN ISO 14001 provinces any individual who ‘s responsibilities may do important environmental harm must be able to conform to the preparation consciousness and competency demands as stated in the EMS. Almost all functions within the building industry will impact on the environment in one manner or another for illustration physical during the building stage or indirectly during the design procedure. Therefore it is critical that each member of an administration regardless of place or function must be cognizant and take duty for environmental direction. In bend this will besides relieve some of the force per unit areas placed upon specialized environmental sections leting them to work more expeditiously. Puting duty across all squad members in this mode can be achieved through preparation, consciousness and communicating strategies that are relevant to the day-to-day patterns of the administration. Through implementing consciousness based EMS ‘s that are compliant with certified criterions administrations may be able to develop a civilization of attention for environmental consciousness and commit to bettering their environmental public presentation. As stated in the authoritiess Strategy for sustainable building, 2008, page 1, â€Å" It is clear that we can non run into our declared environmental marks without dramatically cut downing the environmental impact of edifices and substructure building ; we have to alter the manner we design and build † Purpose The purpose of this thesis is to research the spread between EMS theory and pattern in building and develop schemes for bridging the spread utilizing preparation, consciousness and communicating strategies. Aims What constitutes an EMS? i.e. EMAS, ISO14000 etc. Determine the troubles that are faced when implementing an EMS in the building industry. Investigate the altering relationships between hierarchal degrees and environmental consciousness and how this relationship can impact an administrations environmental public presentation. Identify the normally used schemes for implementing the preparation, consciousness and competency elements of an EMS in building undertakings. Develop a typical preparation strategy that could be used to implement a successful EMS in a site based environment. Methodology Brief description of the methodological analysis used in the survey. Outline Explanation of and debut to the construction of the survey. Chapter 2 – Environmental Management Systems? ISO14001/ EMAS Importance of Environmental Management. Over the past few old ages both public and corporate attending has been drawn towards the negative impacts that humanity is holding on the planet. What is an EMS? Environmental Management Systems are used by administrations to supervise and command any negative impacts that they may hold on the environment. As with most direction systems the chief aim of an EMS is to let relevant information to be conveyed efficaciously through an administration. As Sheldon and Yoxon ( 2006 ) place this allows countries of concern to be assessed with the relevant information in topographic point before the issue can decline. An EMS will normally contains the organizational construction, duties, patterns, processs, procedures and resources for finding and implementing environmental policy ( Netherwood, 1996 ) . Through developing an EMS administrations will be able to place the most important impacts that are relevant to the company. This will in bend allow resources and processs to be focused and prioritised on the issues with the highest demand. The Defra place statement on EMS province that to lend to improved environmental public presentation, a good EMS should: Be implemented at a strategic degree and integrated into corporate programs, and policies. Top-level committedness is required so that senior direction understand their function in guaranting the success of an EMS. Identify the administration ‘s impacts on the environment and set clear aims and marks to better their direction of these facets every bit good as the administration ‘s overall environmental public presentation. Be designed to present and pull off conformity with environmental Torahs and ordinance on an on-going footing, and will rapidly incite disciplinary and preventive action in instances of legal con-compliance. Deliver good resource direction and fiscal benefits. Incorporate assured public presentation prosodies that demonstrate the above and that can be communicated in a crystalline mode in one-year studies. What are the differences between ISO14001, EMAS, etc. ? Administrations that implement standardised EMS ‘s are faced with the determination on which criterions to attest their EMS under. Presently the two most normally used criterions are the European Eco-management and Audit Scheme ( EMAS ) and the worldwide ISO 14001 series. As portion of the ISO household of criterions ISO 14001 is the most recognized and normally enforced system. Further to a recent amendment to EMAS, conformity to ISO 14001 is now required to go certified with EMAS. In add-on to ISO14001 conformity companies must besides carry through extra responsibilities merely ( e.g. cogent evidence of complete legal conformity with national environmental Torahs, and publication of an environmental statement ) to have proof as an EMAS participant every bit good. ( Freimann and Walther, 2002 ) Why implement EMAS? EMAS is a voluntary strategy, therefore the inquiry why would companies take to take part in the strategy must be asked. R. Starkey as edited by Welford ( 1998 ) notes that although full administrations can be in conformity with ISO 14001, merely sites where industrial activities are taking topographic point can be certified by EMAS Administration How does the administration of a company impact their EMS ‘s? Environmental Law and duties EMS jurisprudence developed out of EIA jurisprudence? ? ? ? A common ground for implementing an EMS is due to troubles in keeping environmental due diligence within the parametric quantities of the jurisprudence ( Sheldon, Yoxdon, 2006 ) . During the debut of EMSs they were chiefly centred around maintaining administrations working patterns within environmental statute law and legal conformity ( Watson and Emery, 2007 ) . Although the focal point of EMS may now be towards aˆÂ ¦ it sill remains and of import to place relevant statute law and maintain this at the bosom of the system. Defra ‘s place statement states that a good EMS should be â€Å" designed to present and pull off conformity with environmental Torahs and ordinance on an on-going footing, and will rapidly incite disciplinary and preventive action in instances of legal con-compliance † . It effects over eight different elements of ISO 14001 and even further in EMAS as companies can be â€Å" de-registered † for any breach relevant regulative demands ( Sheldon, Yoxdon, 2006, pg 78 ) . Typically, environmental legislative acts set up a regulative construction consisting of a system of licenses and licenses ( frequently described as â€Å" control and bid † , or â€Å" the right to foul † ) ( Yarnell, 1993 ) . Execution Planing Execution and operation Checking Management Review Environmental Policy Continual Improvement Based on the ISO 14001 theoretical account for execution. Training consciousness and competency How make you mensurate competency? What are the usual or recommended methods of preparation? How cognizant do squad members need to be? Communication Chapter 3 – Research Methodology Aims Qualitative/ quantitative benefits of each Questionnaires Case Study Justification of chosen method What type of research was used? Why was this attack chosen? What type of informations was gained by the research? Who was involved and how were participants selected? What equipment/ instruments were used? Where and when did the probe take topographic point? How was the probe conducted and why was it done this manner? How was data collected, analysed and presented? Phase 1 – Literature research This survey will reexamine the relevant literature on the affair of Environmental direction systems in peculiar looking at execution, care, consciousness, preparation and communicating. Initial research indicates that there is varied scope of literature available to reexamine. This includes legislative publications, text editions, and diaries such as â€Å" Using a communication-mapping theoretical account for environmental direction ( CMEM ) to better environmental public presentation in undertaking development procedures † ( Tam, Shen, Yau, Tam, 2007 ) . Research commence seeking in Athens, INFORMAWORLD, Engineering and Technology, Environmental Engineering, Environmental Management Plans Demystified, Civil Engineering and Environmental Systems Phase 2 – Case Study and Exploratory Questionnaires The inquiries shall center around the countries mentioned in the aims supra. To have the highest possible degree of response, a multi-choice format will be used and the figure of inquiries will be limited to about 20 – 30. Open inquiries will non be used as they can bring forth a broad assortment of replies depending on the respondent ‘s reading of the inquiry. Furthermore, with potentially varied and drawn-out responses, the analyses of the consequences can be well more hard. Phase 3 – Writing up This phase involves composing up the content of the thesis and should cover the chapters proposed below. Chapter 4 – Case Study ( M80 ) Aims M80 Stepps to Haggs overview Reappraisal of Environmental Management Plan Review of other relevant certification Review of Roles and Duties Chapter 5 – Discussion of Finding Reappraisal of literature findings Case Study Does pattern fit literature reappraisal? Gap analysis How can the spread be filled? Chapter 6 – Decisions Recommendations

Evaluation of Montenero Governance and Economic Reforms on the Way to Essay

Evaluation of Montenero Governance and Economic Reforms on the Way to EU Membership - Essay Example This essay presents a comprehensive analysis of modern political and economic developments in Montenegro, which is pursuing its further ties with the EU. Montenegro’s conclusion of its Stabilization and Association Agreement (SAA) negotiation with the European Commission will pave the way for eventual integration with he European Common market . The tiny nation of just 620,000 has done so ahead of Serbia whose European ambitions have been stalled with its refusal to cooperate with the International Criminal Tribunal for the former Yugoslavia. Montenegro looks poised to follow Croatia and Macedonia in actively negotiating accession negotiations. Greater political stability was achieved with the democratic elections held in September in the year 2006 after the narrow win in the referendum in May, with just 55.5% of voters giving a go signal for independence. Djukanovic, with his party in power has even greater leverage to pursue governance reforms in line with democratic principles as one of the main prerequisites into entering the European Union. Held in a fee and fair manner and in line with international standards, the parliamentary elections placed Montenegro was seen favorably by the international community in its capacity to address political reforms and implement them. In terms of legislation, Montenegro has strengthened its anti-corruption drive. Key legislations for improved public procurement and conflict of interest legislation are set to be passed and the Law on Free Access to Information was signed (par 10). Also for the first time as a signal towards greater Montenegro accountability, 1,692 public officials submitted reports on their income and property (par10). Djukanovic in an interview published in the New York Times said that his government managed to pass 140 laws and many more regulations in his past term as Prime Minister, with focus on reforms on the economy, education and administration. As to criticisms that implementation has been slow, he said that the "effects of this reform job will be witnessed only after 5 years" To further cement its legal democratic framework, Montenegro has to craft a

Themes And Ideologies In The American Society Case Study - 1

Themes And Ideologies In The American Society - Case Study Example In Hollywood, the outlaw hero’s view of civilization is portrayed as a life in marriage with a woman. A woman helps a man to settle down and attain calmness in his life. Only those women that allow their husbands to proceed with their self-determined and adventurous lives are deemed as female outlaw heroes. In terms of characterization, the outlaw hero is seen to be against societal standards and in preference of defining justice at the individual level and not by the society’s collective law. Contrary to this, the official hero is more modernized, civilized, and quaint. In his description, Robert Ray points out that the official hero may be portrayed as a lawyer, teacher, farmer, politician, or family man. In this case, the official hero represents collective action as part of the American belief and the legal processes that replace individual definitions of right or wrong. As such, this is the kind of hero that each parent wants their children to grow up to be one who embraces law in solving life’s injustices. This paper review the description made by Robert Ray concerning how Hollywood portrays the competing values of the official hero and the outlaw hero. The outlaw hero is depicted as childish and having the tendency of tantrums, whims, and emotional decisions that have been derived from the cult of childhood among Americans(Ray, 1985). Ray reviews Fielder’s observation of how American literature tends to uphold the view that an individual that falls short of adulthood is guaranteed innocence and insight. American literature offered privileges to children, and they were not confined by societal rules. Such a notion set in motion the outlawed actions as related to daily affairs. According to Fielder, the developed childhood image has created a new approach to adult life outside the law, yet permissible in society.

In the majority of cases plastic surgery not only improves the Essay

In the majority of cases plastic surgery not only improves the external appearance of the person, but it also makes the individual more confident and happier - Essay Example Hence, beauty is regarded by today’s generation as necessary and not a choice. However, not everyone is fortunate to be born with natural external beauty. Nevertheless, the tremendous advancement in the area of medical science has a solution to this problem. Presently, if one has an adequate amount of financial resources one can improve their physical appearance. The method of cosmetic surgery can provide one with an improved external appearance and possibly a better life. Cosmetic surgery is a surgical specialty of medical science that deals with a variety of corrective treatments (Gail, 2000). The objective is to enhance ones outward physical appearance by changing particular features. In the 1990s, people could not even think beyond particular kinds of hair transplant or methods of face-lift or lips enhancement. Presently, one can choose from different beautifying procedures that can improve almost all parts of one’s body, beginning from the head to the feet. With the fast paced advancement in this area of medical science it is not beyond the bounds of possibility to acquire the alluring lips of Beyonce, as it is also not impossible to get the buttocks of Jennifer Lopez. With the assistance of certain surgical methods such as Rhinoplasty or nose surgery, Blepharoplasty or eyelid surgery one can become the owner of an enhanced external appearance. Non-facial cosmetic procedures have likewise become important in defining beauty. Liposuction and breast implants are some of the well known cosmetic procedure that promises one to give an improved outward appearance. Other modern procedures likewise include different kinds of facial implants and chemical face peels that help one maintain a youthful appearance or correct hereditary imperfections. The bottom line is that self confidence is huge factor of success and a beautiful appearance adds to one’s confidence. That is why there is little reason why one should not grab the

Fetishism and the Surrealist Object Essay Example | Topics and Well Written Essays - 1750 words

Fetishism and the Surrealist Object - Essay Example The essay "Fetishism and the Surrealist Object" states Fetishism and Surrealism. Invoking ideas of personal sexual fantasies outsides the realm of polite society, fetishism primarily exists in the world behind the world, and its public expression in the form of art can be a brazen and shocking thing. Contemporary artists such as Mona Hatoum, Rebecca Horn and Nobuyoshi Araki have created significant art that falls into the space of fetishism. However, considering the concurrent societal norms, earlier, less accepting epochs demanding conformity have produced some of the most provocative pieces touching on this taboo, primarily the Surrealists. Indeed, few movements invoke the overall inner landscape of dreams, desires and unconscious more determinedly. Primarily functioning between the two world Wars, Surrealism was a movement motivated by the writings of Andre Breton and dedicated to exposing the desires of the subconscious and fighting the bourgeois society surrounding them in many different avenues of expression. In addition to writing, Surrealist artists utilized painting, collage, photography and sculpture to advance various Freudian driven concepts. Among these was the idea of the object. Although Breton had called for the creation of Surrealist objects earlier, it was only during the 1930’s did the debate and production of these objects truly gain momentum within the group. Distinct from the contemporary concept of sculpture, these homemade montages of distinct yet everyday elements. transferred these works from the utilitarian to the realm of dreams. In this manner, 'the object created therefore constitutes the intrusion into daily life of a desire that moulds and transforms matter according to its requirements, meticulously creating the synthesis of extreme intimacy and the outside world'.4 For this essay I have chosen two famous yet utterly distinct surrealist objects to demonstrate the breadth of fetishism in this movement. Although the "furry teacup" of Meret Oppenheim might seem completely unrelated to Hans Bellmer's notorious doll, they are both objects emerging from the Surrealist school that revolve around fetishism. Object (Le Djeuner en fourrure)5 Introduced to the Surrealist group when she was only eighteen, Meret Oppenheim began as a model for photographer Man Ray before embarking on her Oppenheim, Meret (1936). Object (Le Djeuner en fourrure). Fur-covered cup, saucer and spoon. 7.3 cm tall. On display at The Museum of Modern Art, New York. own artistic endeavours.6 Apparently, the concept for the work emerged from a conversation in a Parisian caf with Pablo Picasso and Dora Maar in 1936:7 he happened to be wearing one of the bracelets she had been making for Schiaparelli out of lengths of fur-lined, polished metal tubing. Talking and joking about the bracelet, Picasso quipped that one could actually cover anything with fur, to which Meret replied, "Even this cup and saucer" Shortly afterwards, When Andr Breton invited her to contribute to an Exhibition of Surrealist objects at the Galerie Charles Ratton, she recalled the conversation and, without further ado, bought a large cup and saucer with spoon at the Parisian department store, Uniprix, and lined the three objects with the fur of a Chinese gazelle. It was Andre Breton who named the work.8 Somehow, this simple concept erupted into the canons of twentieth century art, and what

Chanticleer show ( jazz) Essay Example | Topics and Well Written Essays - 500 words

Chanticleer show ( jazz) - Essay Example However, the group generates substantial incomes from major global events and album sales (Weir, & Alfred Publishing Co. 2008). The following is an intense discussion on Chanticleer Jazz Show, with a reflection of the music genres, advancements, and revenue creation tactics. In the Grammy Awards ceremony, Chanticleer acquired an acknowledgement as the reigning global male chorus ahead of many other groups. Further, the group yields praise from its global audience and the media outlets. Over the past three decades, the group has continually blended the jazz music genre from an earlier and stagnant phase. Chanticleer is renown in San Francisco as an orchestra of voices, a factor that emanates from the combination of twelve members with unique voices. Their sales performances are overwhelming and consequently are leading in San Francisco (Weir, & Alfred Publishing Co. 2008). Opening with the songs, â€Å"The Siren’s Call†, and â€Å"Temptations†, Chanticleer Jazz show attracted a huge audience from all the American states. The countrywide tour in the U.S impacts effective reputation from the fans, and a probability is that the expected turnover at the events shall be overwhelming. As at March of 2013, the group targets to launch the anniversary tour, starting in New York City and spreading to other parts of the world. Chanticleer schedules to travel globally in an effort to complete the planned hundred concerts and performances. The tour will improve on the perceptions held on Jazz music. For example, a reflection of the 2011-2012 tour led to the birth of a music choir –The Louis A. Botto Choir. Therefore, presumptions are that the group serves as a motivating factor to rekindle and improve Jazz music, with a surety that the music genre will successfully pass to future generations. Another aspect that possibly reveals Chanticleer as a promotional choir to ensuring survival of Jazz is the fact that, the group focuses on encourages teenagers

Factor behind the fall of communism in Eastern Europe Essay

Factor behind the fall of communism in Eastern Europe - Essay Example Communisms can also be well-defined as the principle of the circumstances of the public or waged people. This is a category of people in the society who live totally from the sale of their labour without profit and capital gains.   The proletariat in a word is the working class of the 19th  century. The lay man’s understanding of communism is that it is the rule of the gun in which the elite minority control the masses through all manner of oppression and exploitation, it started in 1945 and ended in 1991. Before the end of cold war in 1991 the world was divided into two blocs the Eastern and the Western (Western Europe and America). The Eastern Bloc which was the communist comprised of the Soviet Union, Poland, Czechoslovakia, Romania, East Germany, Hungry and Yugoslavia, with Poland being the largest communist country  apart from the Soviet Union however there were other communist  countries outside Europe such as Cuba (Levesque, 2010, p. 7). Many factors were respon sible for the collapse of communism, in this essay only three are explored namely nationalism, economic and ideology. Great emphasis is placed on economic as the main cause that affected Eastern Europe. Communism collapsed in 1989 and the iron curtain was dismantled with the demolition of the Berlin wall (Zubok, 2010, p.7). A long period of silence existed known as the cold war and set the world in two separate blocs the western and the eastern plus their allies. The standoff resulted into tension, suspicion, anxiety and fear among the rivaling blocs. An opaque situation existed known as the Iron Curtains that promoted heinous acts of oppression, nepotism, corruption and lack of accountability between the two blocs. This resulted into separation of Europe with a manmade Berlin wall. The insecurity and tension felt on both sides led to the nuclear arms race giving rise to the development of defense organizations in Europe i.e. the WARSAW pact and the NETO (Howard, 2003, p. 10). Befor e looking at the factors that led to the overthrow of communism

The First World War Essay Example for Free

The First World War Essay In this report I intend to create a detailed report of Tescos. I want to see what they have done to get to where they are today and to try to evaluate why what they did worked. I want to get as much information as possible, although some information may not be accessible to the public as it could be sensitive. After the First World War, Jack Cohen received a i 40 gratuity. With this he set up his own East end fruit and veg store. Later he joined with another man T. E Stockwell to create a partnership. They then formed a limited company and now Tesco is a public limited company (PLC) with an annual turn over of around i 30,814 million pounds. When Cohen set up Tesco, he was a sole trader, he would have had unlimited liability. This means that if he went bust and unable to pay his debts he would have his personal belongings sold by the bank to pay off his debts. His only source of finance was his i 40 war gratuity. However nowadays there are many different sources of finance from bank loans to business angles to loan sharks as well as personal savings and family and friends. Being a sole trader has many advantages as there arent many forms to fill in. You can take holidays when you want and all the money that is made in the form of profit is yours for the keeping. Being a sole trader means that he had total control over his business all profit made goes straight to him and doesnt need to be split up. When he merged to form a partnership he would have had to sign a deed of partnership. This outlines all main points about the partnership from money salaries to working hours. He would now have to consult his partner before making any decisions about the business. However there are good points about being in a partnership. It means that there are two or more people to help think a way around a problem should one occur. It would bring added finance as the other partner would have personal savings and maybe family money. If the partnership were to go bust the deed of partnership would outline who had to pay what debts. After the partnership became successful Cohen and Stockwell became an ltd company. This means that they had shares which could be sold to employees and friends and family of the owners. They effectively own a small part of the company. They now have Limited liability this means that should the business go bust their private possessions are now safe and wouldnt be sold to level debts. Yet all the share holders would loose the amount of money they put in. There are also disadvantages to go with the benefits; these are that accurate accounts now have to be published for company house. This means spending money on an accountant. Tescos then became a plc or public limited company, it floated on the stock market in 1947 the share price was 25p. The business is now controlled by the share holders as every share gives you a say in the company. The profit is also split so that a dividend can be given to the share holders; this is a small percentage of profit given to share holders, and the more shares the more money they will receive. The legal liabilities are the same as when they were an ltd. The main difference is that shares can be bought and sold by the public on the stock exchange. On the way up Tescos has been through many of the different types of businesses. It has been a sole trader business a partnership an ltd company and now its a plc. However there are a few types of business that Tescos hasnt been. * A charity: this is obviously because Tescos is a profit organisation and wouldnt want to give away all there profit.

Solid Dispersion System in Drug Delivery

Solid Dispersion System in Drug Delivery The oral route remains the preferred route of drug administration due to its convenience, good patient compliance and low medicine production costs. In order for a drug to be absorbed into the systemic circulation following oral administration, the drug must be dissolved in the gastric fluids. The active pharmaceutical ingredient in a solid dosage form must undergo dissolution before it is available for absorption from the gastrointestinal tract.1 Currently, approximately 40% of the marketed immediate release (IR) oral drugs are categorized as practically insoluble ( 1.1 Biopharmaceutics classification system The Biopharmaceutical Classification System (BCS) was introduced in the mid-1990s to classify the drug substances with respect to their aqueous solubility and membrane permeability. BCS is a useful tool for decision-making in formulation development from a biopharmaceutical point of view. Solubility improvement strategies are required for Class II and Class IV drugs. 1.2 Approaches to improve the solubility or to increase the available surface area for dissolution Physical modifications Particle size Micronization Nanosuspensions Modifications of the crystal habit Polymorphs Pseudopolymorphs (including solvates) Complexation/solubilization Use of surfactants Use of cyclodextrins Drug dispersion in carriers Eutectic mixtures Solid dispersions (non-molecular) Solid solutions Chemical modifications Soluble prodrugs Salts 1.3 Solid Dispersions The term solid dispersion refers to a group of solid products consisting of at least two different components, generally a hydrophilic matrix and a hydrophobic drug. The matrix can be either crystalline or amorphous. The drug can be dispersed molecularly, in amorphous particles (clusters) or in crystalline particles.7 Much of the research that has been reported on solid dispersion technologies involves drugs that are poorly water-soluble and highly permeable to biological membranes as with these drugs dissolution is the rate limiting step to absorption. Hence, the hypothesis has been that the rate of absorption in-vivo will be concurrently accelerated with an increase in the rate of drug dissolution. Therefore, solid dispersion technologies are particularly promising for improving the oral absorption and bioavailability of BCS Class II drugs. 1.3.1 Types of solid dispersions On the basis of release mechanisms and molecular arrangement in the matrix, solid dispersions are distinguished into following types9: A. Simple eutectic mixture: Eutectic mixture is prepared by rapid solidification of fused melts of two components that show a complete liquid miscibility with negligible solid-solid solubility. It involves loose atomic or molecular interaction and not on the formation of chemical bonds. When the eutectic mixture is exposed to gastrointestinal fluids, both the poorly soluble drug and the carrier may simultaneously crystallize out as a very small particles result in an increased the surface area and improved dissolution and absorption of the drug. B. Solid solution: A solid solution represents a homogenous one phase system, where the solid solution is dissolved in a solid solvent and the two components crystallize together. The solid solution achieves faster dissolution than a eutectic mixture because the drug particles in a solid solution are reduced to molecular size and dissolution of the drug takes place in the solid state prior to the exposure to the liquid medium. C. Glass solution: It is a homogenous glassy system in which a solute dissolves on glassy solvent results in increased dissolution and absorption of the drug. It is characterized by a transparency and brittleness below the glass forming temperature. Glass solution is a metastable and the strength of the chemical bonding is much less as compared to solid solution. Therefore, the release of the drug was found to be faster than a solid solution. D. Amorphous precipitations in crystalline carrier: An amorphous form of a drug produces faster dissolution rate. The drug may precipitate out in an amorphous form in a crystalline carrier from solid dispersions prepared by melting or solvent method. A strong interaction between the drug and carrier resulting in the formation of channels within the matrix seems to be a possible mechanism for improved dissolution of the drug. E. Compound or complex formation: The formation of a complex between the drug and the carrier may either decrease of increase the dissolution and the absorption rate of the drug. The formation of soluble complex with low association constant resulted in increased rate of dissolution and absorption. The enhancement in dissolution rate of the drug can be ascribed to An increasing solubility of the drug because of its amorphous state or small particle size (Kelvins law)9,10 An increased surface area available for drug dissolution because of the small size of the drug particles11,12 An improvement in wetting of the drug caused by the hydrophilic carrier13,14 1.3.2 Advantageous properties of solid dispersions Management of the drug release profile using solid dispersions is achieved by manipulation of the carrier and solid dispersion particle properties. Parameters such as carrier molecular weight and composition, drug crystallinity and particle porosity and wettability, when successfully controlled, can produce improvements in bioavailability.16 a. Particles with reduced particle size: Molecular dispersions, as solid dispersions, represent the last state on particle size reduction, and after carrier dissolution the drug is molecularly dispersed in the dissolution medium. Solid dispersions apply this principle to drug release by creating a mixture of a poorly water soluble drug and highly soluble  carriers. A high surface area is formed, resulting in an increased dissolution rate and consequently, improved bioavailability. b. Particles with improved wettability: Strong contribution to the enhancement of drug solubility is related to the drug wettability improvement in solid dispersions. It was observed that even carriers without any surface activity, such as urea improved drug wettability. Carriers with surface activity, such as cholic acid and bile salts, when used, can significantly increase the wettability properties of drugs. Moreover, carriers can influence the drug dissolution profile by direct dissolution or co-solvent effects. c. Particles with higher porosity: Particles in solid dispersions have been found to have a higher degree of porosity. The increase in porosity also depends on the carrier properties, for instance, solid dispersions containing linear polymers produce larger and more porous particles than those containing reticular polymers and, therefore, result in a higher dissolution rate. The increased porosity of solid dispersion particles also hastens the drug release profile. d. Drugs in amorphous state: Poorly water soluble crystalline drugs, when in the amorphous state tends to have higher solubility. The enhancement of drug release can usually be achieved using the drug in its amorphous state, because no energy is required to break up the crystal lattice during the dissolution process. 1.3.3. Carriers used in solid dispersions Many carriers of natural, semi-synthetic and synthetic types are being used which include natural carbohydrates, semi-synthetic and synthetic hydrophilic polymers. S.No:  1 Nature of carrier:  Sugars Name of the carrier:  Dextrose, sorbitol, sucrose, fructose,maltose,galactose, xylitol, mannitol S.No:  2 Nature of carrier:  Acids Name of the carrier:  Citric acid, tartaric acid and succinic acid S.No:  3 Nature of carrier:  Polymorphic materials Name of the carrier:  Polyvinyl pyrrolidone (PVP), polyethylene glycols, hydroxyl propylmethylcellulose (HPMC), guargum, xanthan gum, sodium alginate, methyl cellulose, pectin, hydroxyl ethyl cellulose (HEC), hydroxyl propyl cellulose (HPC) and dextrins. S.No:  4 Insoluble or enteric Nature of carrier:  polymer Name of the carrier:  Hydroxy propyl methyl cellulosepthalate, eudragit RL, eudragit L 100, eudragit S100, eudragit RS. S.No:  5 Nature of carrier:  Surfactants Name of the carrier:  Polyethylene stearate, poloxamer 188, tweens and spans. S.No:  6 Nature of carrier:  Miscellaneous Name of the carrier:  Nicotinic acid, succinamide, dextrans, gelatin, poly vinyl alcohol, urea, cyclodextrins, skimmed milk etc., Table 1.2 Various carriers used in solid dispersions 1.3.4. Preparation techniques of solid dispersions The following are the major processes for the preparation of solid dispersions. A. Solvent evaporation method: In this method, the physical mixture of two components is dissolved in a common solvent and followed by the evaporation of solvent. The advantages of this method are low temperature requirements for the preparation of dispersion and thermal decomposition of drugs and carriers can be prevented. The higher cost of production, incomplete removal of solvent, adverse effects of solvent on the chemical stability of the drug and selection of common solvent are the drawbacks of this method. B. Melting method (Fusion method): The physical mixture of drug and water- soluble carrier was heated to melt and the molten mixture was then cooled and solidified mass was crushed, pulverized and sieved. The melting point of a binary system depends on its composition and proper manipulation of drug carrier ratios. Decomposition should be avoided due to fusion time and the rate of cooling. C. Kneading method: The physical mixture of drug and carrier were triturated using small quantity of organic solvent and water mixture, usually alcohol and water (1:1v/v). The slurry is kneaded for 45 minutes and dried at 45 °C. The dried mass is pulverized and sieved through sieve no. 60 and the fraction was collected. The advantages of this method are low temperature requirements for solid dispersion preparation and usage of organic solvent is less. This method of preparation avoids thermal degradation of drug and employs less quantity of organic solvents. D. Melting solvent method: This method involves dissolving the drug in a suitable solvent and the incorporation of the solution directly into the molten carrier. This method possesses the advantages of both solvent and melting methods. E. Supercritical fluid methods: Supercritical fluid methods are mostly applied with carbon dioxide (CO2), which is used as either a solvent for drug and matrix or as an antisolvent. This technique consists of dissolving the drug and the carrier in a common solvent that is introduced into a particle formation vessel through a nozzle, simultaneously with CO2. When the solution is sprayed, the solvent is rapidly extracted by the SCF, resulting in the precipitation of solid dispersion particles on the walls and bottom of the vessel. This technique does not require the use of organic solvent and since CO2 is considered environmentally friendly, this technique is referred to as solvent free. This technique is known as Rapid Expansion of Supercritical Solution (RESS). F. Lyophilization/ Freeze Drying: This technique is an alternative to the solvent evaporation method. Here the drug and carrier are dissolved in common solvent, frozen and sublimed to obtain a lyophilized molecular dispersion. G. Melt agglomeration process: This technique is used to prepare solid dispersion where a binder acts as a carrier. The solid dispersion is prepared by heating binder, drug and excipient to a temperature above the melting point or spraying the dispersion of drug in the molten binder on the heated excipients using a high shear mixer. The effect of binder type, method preparation and particle size are the critical factors influencing the solid dispersion preparation by this method. These parameters results in various dissolution rates, mechanism of agglomerate formation and growth, agglomerate size and distribution. 1.3.5. Limitations of solid dispersion systems: Problems limiting the commercial application of solid dispersions are: Laborious and expensive method of preparation. Reproducibility of physico-chemical characteristics. Difficulty in incorporating into the formulation of dosage forms. Crystallization of the amorphous drug in the dispersion. Poor scale up of manufacturing process and physical and chemical stability of drug and the vehicle. 1.4 FDTs: Fast-disintegrating and fast-dissolving tablets are becoming popular as novel delivery systems for drug administration. They are more convenient for children, elderly patients, patients with swallowing difficulties, and in the absence of potable liquids. The most desirable formulation for use by the elderly is one that is easy to swallow easy to handle. Taking these requirements into consideration, attempts have been made to develop a fast-disintegrating tablet. Since such a tablet can disintegrate in only a small amount of water in the oral cavity, it is easy to take for any age patient, regardless of time or place. For example, it can be taken anywhere at anytime by anyone who do not have easy access to water. It is also easy to dose the aged, bedridden patients, or infants who have problems swallowing tablets and capsules. Recently, many companies have researched and developed various types of fast-disintegrating dosage forms.18 These tablets display a fast and spontaneous de-aggregation in the mouth, soon after the contact with saliva, though they can be handled or extracted from the package without alteration. The active agent can thus rapidly dissolve in the saliva and be absorbed through whatever membrane it encounters, during deglutition, unless it is protected from pre-gastric absorption. To fulfill these requirements, tablets must be highly porous, incorporating hydrophilic excipients, able to rapidly absorb water for a rapid deaggregation of the matrix. Different technological techniques, such as freeze drying or molding or direct compression are currently employed to prepare the formulations of this type present on the pharmaceutical market. 1.4.1 Advantages of Fast Disintegrating Drug Delivery System (FDDS) 19,20 Ease of administration to patients who refuse to swallow a tablet, such as pediatric and geriatric patients, mentally ill, disabled and uncooperative. Convenience of administration and accurate dosing as compared to liquids. No need of water to swallow the dosage form, which is highly convenient feature for patients who are traveling and do not have immediate access to water. Good mouth feel property of FDDS helps to change the basic view of medication as bitter pill, particularly for pediatric patients. Ability to provide the advantages of liquid medication in the form of solid preparation. Rapid dissolution of drug and absorption, which may produce rapid onset of action. Some drugs are absorbed from the mouth, pharynx and oesophagus as the saliva passes down into the stomach; in such cases bioavailability of drugs is increased. Pregastric absorption can result in improved bioavailability and as a result of reduced dosage, improved clinical performance through a reduction of unwanted effects. 1.4.2 Approaches for fast disintegrating tablets A. Patented technologies Currently, four fast-dissolving/disintegrating technologies have reached the U.S. market: Zydis (R.P. Scherer, Inc.) WOWTAB (Yamanouchi Pharma Technologies, Inc.) OraSolv (Cima Labs, Inc.) DuraSolv (Cima Labs, Inc.) B. Three others are available outside the U.S. Flash Dose (Fuisz Technologies, Ltd.), Flash tab (Prographarm Group), OraQuick (KV Pharmaceutical Co., Inc.) Nanocrystal Technology C. Conventional technologies Freeze -drying or lyophilization Tablet Molding Direct compression Spray drying Sublimation Mass extrusion Direct compression It is the easiest way to manufacture tablets. Conventional equipment, commonly available excipients and a limited number of processing steps are involved in direct compression. Also high doses can be accommodated and final weight of the tablet can easily exceed that of other production methods. Directly compressed tablets disintegration and solubilization depends on the single or combined action of disintegrates, water soluble excipients and effervescent agent. Disintegrate efficacy is strongly affected by tablet size and hardness. Large and hard tablets have a disintegration time more than that usually required. As consequences, products with optimal disintegration properties often have medium to small size and /or high friability and low hardness. Breakage of tablet edges during handling and tablet rupture during the opening of blister, all results from insufficient physical resistance. Disintegrants have a major role in the disintegration and dissolution process of mouth dissolving Tablets made by direct compression. To ensure a high disintegration rate, choice of suitable type and an optimal amount of disintegrant is important. Other formulation components such as water soluble excipients or effervescent agents can further enhance dissolution or disintegration properties. But the main drawback of using effervescent excipients is their highly hygroscopic nature. The understanding of disintegrant properties and their effect on formulation has advanced during the last few years, particularly regarding so called superdisintegrants. Disintegration efficiency is based on a force equivalent concept, which is the combined measurement of swelling force development and amount of water absorption. Force equivalent expresses the capability of disintegrant to transform absorbed water into swelling force. The optimization of tablet disintegration was defined by means of disintegrant critical concentration. Below this concentration, the tablet disintegration time is inversely proportional to disintegrate concentration and above that disintegration time remains approximately constant or even increases. The simultaneous presence of disintegrate with a high swelling force called disintegrating agent and substances with low swelling force ( starch, cellulose and direct compression sugar) defined as, swelling agent was claimed to be a key factor for the rapid disintegration of the tablet, which also offers physical resistance. 1.4.3 Mechanism of tablet disintegration and water absorption When mouth dissolving tablets placed in the mouth, upon contact with saliva the tablet disintegrates or dissolve instantaneously. The mechanisms involved in the tablet disintegration mechanisms are Swelling Wicking (capillary) Deformation Particle repulsive forces Chemical reaction (acid base reaction) a. Swelling Not all disintegrates swell in contact with water swelling is believed to be a mechanism in which; certain disintegrating agents (like starch) impart their disintegrating effect. By swelling in contact with water, the adhesiveness of other ingredients in a tablet is overcome causing the tablet to disintegrate. b. Wicking (porosity and capillary action) Effective disintegrants that do not swell are believed to impart their disintegrating action through porosity and capillary action. Tablets porosity provides a way for the penetration of fluid into tablets. The disintegrants particles (with cohesiveness and compressibility) themselves act to enhance porosity and provide these capillaries into the tablets. Liquid is drawn up or wicked into these ways by capillary action and rupture the inter-particulate bonds causing the tablet to break into small parts. c. Deformation Starch grains are generally thought to be elastic in nature that is the grains that are deformed under pressure will return to their original shape when that pressure is removed. But, with the compression forces involved in tabletting, these grains are permanently deformed and are said to be energy rich with these energies being released upon exposure to water, that is the ability for starch to swell is higher in energy rich starch grains than in starch grains that have not been deformed under pressure. It is believed that no single mechanism is responsible for the action of most disintegrants. But rather, it is more likely the results of interrelationships between these major mechanisms. d. Due to disintegrating particle/particle repulsive forces: Another mechanism of disintegration attempts to explain the swelling of tablets made with non-swellable disintegrants. Guyot-Hermann has proposed a particle repulsion theory based on the observation that nonswelling particle also causes disintegration of tablets. The electric repulsive forces between particles are the mechanism of disintegration and water is required for it. Researchers found that repulsion is secondary to wicking. e. Chemical reaction (acid base reaction) Disintegration of tablet included with citric acid and tartaric acid along with the sodium bicarbonate, sodium carbonate, potassium carbonate; these react in contact with water to liberate carbon dioxide that disrupts the tablet. Name of the Product:  Imodium Lingual Active Ingredients:  Loperamide hydrochloride Dose:  2 mg Name of the Product:  Pepcidin Rapitab Active Ingredients:  Famotidine Dose:  20mg and 40 mg Name of the Product:  Mosid MT Active Ingredients:  Mosapride citrate. Dose:  2.5mg and 5mg Name of the Product:  Calritin Reditabs Active Ingredients:  Loratadine Dose:  10 mg Name of the Product:  Nimulid MD Active Ingredients:  Nimesulide Dose:  50mg and 100mg Name of the Product:  Zyrof Meltab Active Ingredients:  Rofecoxib Dose:  50 mg Name of the Product:  Feldene Melt Active Ingredients:  Piroxicam Dose:  10mg and 20 mg Name of the Product:  Maxalt-MLT Active Ingredients:  Rizatriptan Dose:  5mg and 10 mg Name of the Product:  Pepcid RPD Active Ingredients:  Famotidine Dose:  20mg and 40 mg Name of the Product:  Zyprexa Zydis Active Ingredients:  Olanzapine Dose:  5mg, 10mg, 15mg and 20 mg Name of the Product:  Zofran ODT Active Ingredients:  Ondansetron Dose:  4 mg and 8 mg Name of the Product:  Remeron Soltab Active Ingredients:  Mirtazepine Dose:  15mg, 30mg and 45 mg Name of the Product:  NuLev Active Ingredients:  Hyoscyamine sulfate Dose:  0.125 mg Table 1.3 Marketed fast disintegrating tablets Piroxicam, a non-steroidal anti inflammatory agent, belonging to BCS class II is widely used as a first line drug in the symptomatic relief of rheumatoid arthritis and osteoarthritis. Its low aqueous solubility has to be overcome through formulation strategies. Skimmed milk can be used as a drug carrier as it is inexpensive, easily available, biodegradable, and does not exhibit toxicity problems as experienced with PEG and PVP.24-26 Polymers  as  carriers  also  have  limitations  in  enhancing  Ã‚  the  Ã‚  solubility  of poorly  soluble drugs  due to  their  high viscosity. So the use of skimmed milk in the formulation of the SD of the drugs with limited aqueous solubility may be a potential and cost effective way to overcome the problem.27 Skimmed milk is a colloidal suspension of casein micelles, globular proteins and lipoprotein particles. The principal casein fractions are a-s1, a-s2, b-casein and k-casein. b-casein is amphiphilic and acts as a detergent molecule with surfactant property. The milk also contains whey proteins with principle fractions of the b-lacto globulin, a-lactalbumin, bovine serum albumin and immunoglobulins. These molecules were found to be surface active with a superior solubility than caseins.28 Aminoacids have been suggested either as additives in peroral application or in the form of aminoacid salts to reduce gastrointestinal disorders arising due to piroxicam like NSAIDs. The surface active agents and amino acid content are expected to be the reason for increased permeation of the drug from the solid dispersion.29,30

The issues faced by Greyhound Lines

The issues faced by Greyhound Lines Greyhound Lines, Inc. is the one and only countrywide contributor of intercity bus service in the United States. Its task force of 2,400 buses brings further than 22.5 million travelers every year in excess of a road system that lengthen for further than 75,000 miles. Greyhound schedule to further than 2,600 destinations, with 18,000 on a daily basis leaving. Additionally to its programmed traveler services, the corporation suggests charter bus service, express package service in the course of Greyhound Package Express, and food service at a number of its workstation. Greyhound is also caught up in cross-border bus service throughout joint ventures with Mexican transportation businesses. The bus company that develops into Greyhound was created in 1913 by Carl Earl Wickman. The secret to Wickmans early on achievement was making best use of ridership, which took the appearance of padding 18 miners into a seven-passenger Hupmobile. Wickmans revenues start on to boost, and he took on bus iness buddies who lend a hand for him in supply funds in bigger bus SUMMARY Greyhound Lines is the nations largest bus company. However, they face a big problem when they start to introduce computerization system in the business. The problem became a major problem to their company because they took the wrong part in making decision just to increase profit and customer service. The top level manager face financial problems by introducing computerize system in their business without taking into the middle level managers opinion. Greyhound was facing non-programmed decision problem where the top level managers take a precise solution for an exceptional problem. The software called Trips software. There were problems such as the customers dont have credit card or telephone to make use of Trip software. Furthermore, the software sometimes not working and it take time to print the ticket out, this make the customer frustrated for waiting in line for so long. Was the decision facing Greyhound executives programmed or non-programmed? Programmed decision means resolution previously obtainable from earlier period knowledge to resolve troubles that are well-known, clear-cut, and obvious with value to information requirements. These judgments relate finest to problems that are subject of custom, even though it is not unsurprising but they can predict. However, non-programmed decision means relate precise way out ability for an only one of its kind problem. the majority problems handle by advanced rank manager are of this kind, with the problems frequently concerning alternative of tactic and purpose in situation of some doubt. Therefore, Greyhound is facing non-programmed decision. There are three type of non-programmed decision such as re-organization, computerization, and improve customer services. Firstly, re-organization means a renovation of a company business, as well as a obvious transform in resources formation, over and over again subsequent a disappointment and receivership or liquidation trusteeship. Greyhound Lines face re-organization when they introduced computerize system in their business. Some of their customers dont know how to use a credit card or telephone to call to book a ticket for them. This have cause the operators receive many calls from their customer about they dont know how to use the software and they cant get access to the Trip software. Secondly, computerization is a factor of non-programmed. Computerization means to control, perform, process, or store (a system, operation, or information) by means of or in an electronic computer or computers. The customer cant access to the software so they customer directly come to the ticket selling place to buy the ticket. However, when the customers try to buy the ticket, they have to wait for 5 minute and 45 second to the computer to process and print the ticket. These causes the number of customer wait to buy ticket decrease because they feel angry to wait for so long to buy a ticket. Thirdly, Greyhound also has to improve customer service to solve the problem that the company is facing now. Customer services means expanding our thinking about customer service; if were going to consistently exceed customers expectations, we have to recognize that every aspect of our business has an impact on customer service, not just those aspects of our business that involve face-to-face customer contact. Greyhound has been overwhelmed by plentiful customer criticism, as well as constantly not on time buses, impolite employees, unhygienic services, insecure environment, mechanical breakdown and accidents. Buses have been recognized to get there quite a lot of hours after their programmed arrival time and employees have been unconcerned and even orally insulting of passengers who ask over for assist. This is one of the reason that the top level decide to introduce computerize system. In conclusion, There are three type of non-programmed decision such as re-organization, computerization, and improve customer services. Greyhound can learn from the experiences of others to solve this problem. Two very common mistakes company make when breakdown organizational change are they try to manage on their own and they fall short to advantage from the knowledge of others. Thousands of bus organizations maybe have faced circumstances similar to Greyhound. So they can try to have a discussion to these knowledgeable people. Pick their intelligence. Discover out what other people in Parallel Corporation are responsible to deal with downsizings or development. They also can study books and articles about these problems. QUESTION 2 Do you think Greyhound should have used the classical, administrative, or political model to make decision? Which do you believe it used? Discuss. Provide examples to justify your answer. The classical management approaches focal point on budding general standard for applies in a variety of organization circumstances. However, administrative management approaches means center of attention on human being requirements, the work group and the position of community feature in the place of work. In the other hand, political management approaches means focus on put into operation mathematical method for administration of crisis solving. Greyhound uses classical model then the other two models. There are three types of classical approaches such as scientific management, administrative principle, and bureaucratic organization. Firstly, scientific management means highlight cautious selection and training of workers, and decision-making support. This management is found by Frederick Taylor and Frank and Lilian Gilbreth. There four guiding action principles that Greyhound have used to improve their business. First of all, develop for each job a science that contain regulations of movement, consistent work progression and appropriate working circumstance, then they have to choose workers with the exact skill for the occupation, cautiously coach workers to do the job and offer them the suitable encouragement to work together with the job science, and maintain workers by carefully scheduling their job and by level the method as they go regarding their jobs. Greyhound should plan properly for the employees to what have to be done in specific given time. Greyhound should make the employees feel like home in their working place so that the employees do the work in time. Secondly, administrative principle is based on effort to file and be aware of the skill of victorious managers. This principle developed by Henry Fayol and Mary Parker Follet. There five important point in this principle. First of all, Greyhound have to foresight which means they have to complete a plan of action for the expectations where they should have plan A and plan B so that if one plan fail then they can go for the second plan. Then, Greyhound has to offer and assemble resources to implement the plan. So Greyhound has to be preparing in financial way and equity way to achieve their future plan. Furthermore, Greyhound has to control to guide, decide on, and appraise workers to get the most excellent work towards the plan for example employees is one of the most important source that going make these idea into reality so Greyhound has to very careful in choosing their employees so that Greyhound can move into future plan then just sit around worrying about employees attitudes t o customers. Moreover, coordination and control can make sure the work goes according to the plan. Thirdly, bureaucratic organization is a balanced and well-organized structure of organization establish on common sense, regulate and lawful power. There are five factors in bureaucratic such as clear division of labor, clear hierarchy of authority, formal rules and procedures, impersonality, and career based on merit. Greyhound have to define very clearly what the employees have to do then the worker have to report to higher level people after that the higher level people have to a report of the work. If the employees follow the rules and regulation properly and did their work then the managers have to reward the employees to boost the employees to do better than now. In conclusion, Greyhound has to plan properly, if they want to invent computerization in the company. Employees is one of the most important people in making the company success internal so Greyhound have to give time to for the employees to celebrate their accomplishments. Futhermore, there are Christmas festivity in December to do party and the yearly corporation picnic in the summer for the employees to enjoy their movement with their higher level people. This can be surprised for Greyhound on how a great deal of a difference this can create. QUESTION 3 Analyze the Greyhound case in terms of the steps in the managerial decision making process. Do you think top executive paid adequate attention to all the steps? I f you were a Greyhound, what would you do now and why? Decision making means the procedure of making selection among other path of action. There are five stepladders in decision making which is very important for business. This decision creation representation in five steps is a common but extremely successful outline for making decisions and put an end to problems. This discipline will help prevent Greyhound from receiving unfocused on a number of small elements of the significant steps leading to a decision. Firstly, Greyhound has to identity and defines the problem that they are facing. In anticipation of Greyhound have an obviously thoughtful of the dilemma or decision to be made, it is worthless to continue. If the problem is stated the wrong way or indistinguishably then Greyhounds result will be incorrect. Greyhound didnt consider what the middle manager is thinking such as the employees are very rude to the customer, then Greyhound implement computerize system to solve the first problem, however, the top level didnt think about the customer who dont know how to use the software and Greyhound didnt test the software before implementing which cause the customer cant buy ticket in that software. Moreover, after everything being computerizes the customer have to wait so long in queue to buy ticket for their journey. Secondly, Greyhound has to generate and evaluate possible solution to solve the problem that they are facing. Greyhound should have know that there is possible whether to do it or dont do it when they want to implement something new in the business. Most of the time Greyhound should know that there will possible substitute for their decision. It is worth for Greyhound doing research to ensure whether they have as many good alternatives as possible. For example, Greyhound implement customer service to take care of the customer problem with the employees or Greyhound can send the entire employee to a course which teaches them how to be polite to customer. Furthermore, if Greyhound wants to implement computerize system in their business then they should test all the software available in market before choosing one of the software which is the best one. Thirdly, Greyhound has to choose a solution to solve the problem. Then main problem is the employees treated the customer very badly and implementing computerizes system so Greyhound can have a department especially for the customer to complain about their dissatisfaction and Greyhound has to do research first before choosing software. Then Greyhound has to implement the solution which means they have to put their plan into work. Finally, they have to evaluate the result whether it satisfied the customer. Greyhound can do survey whether the customer satisfied with the service that they provide. As customer is the most important people in helping the business increase their revenue. CONCLUSION In conclusion, although Greyhound faces a serious problem in introducing computerize system in their business especially Trip software which cause Greyhound suffer losses in their business. However, they still manage to overcome the problem by changing high-speed Kodak scanners are used to scan the large volume of data. This optimized high-speed scanning software was developed by Combined Computer Resources, Inc which helps Greyhound overcome their problem and increase the business profit. Being creative is one of the most excellent habits to deal with managerial transform is to rev up the managers natural powers for creative intervention. Most problems are amenable to creative, innovative solutions. The only things that frequently persist in this resolution from occur is the Greyhounds own inner obstacle and nature obligatory boundaries. Creative crisis resolve all the time contain jeopardy. Suggesting fresh thought summons disapproval from others. What if the plans not succeed? Wha t if business losses take place? What if things wind up worse than previously? They got to be enthusiastic to understand such risks if they are going to be free to think creatively. (1800 words)

A Pharmacist :: essays research papers

A Pharmacist Being a pharmacist is much harder than what you probably thought it was. Pharmacists in a hospital have many, many responsibilities. They must be very careful that they have measured the medication correctly, because one little mistake can be potentially fatal. Pharmacists must know what many of the medications do, and if there are any side effects and incompatibilities with other medications the patient might be on. For example, a person might be taking a medication for another problem, and if the physician and pharmacist don't notice that condition, the prescribed medication might cause a deadly interaction. This does not happen with all drugs, but it happens with a few, and you certainly don't want a result like that. The pharmacist must also make sure that the patient does not have any allergies against that type of medication. Pharmacists should also know generic brands of medication that might save the patient's money. They must know any differences between the brand name and the generic name, such as drug interactions, side effects, and how it should be taken. Some responsibilities of the pharmacist include making intravenous solutions and operating the TPN, which takes intravenous solutions and adds vitamins such as amino acids. They also refill storage bins in the Emergency Room, where doctors can get them if a patient needs them immediately. Charles Rudolph Walgreen Sr. Is the founder of Walgreens. When he was twenty, he borrowed twenty dollars, and moved from Dixon, Illinois to Chicago. Throughout pharmacy school, he worked for pharmacies in the day and went to school at night. When the United States went to War with Spain in 1898, Walgreen was enlisted as a private. There were many diseases in Cuba, and Walgreen fell sick. The doctor was so sure that Walgreen was going to die, that he put Walgreen's name on the casualty list, and newspapers told of his death! When Walgreen returned from the war, he worked as a pharmacist for a man by the name of Isaac W. Blood. He later bought out Blood's pharmacy. Customer service was very important to Walgreen. Often, he would answer the phone himself, then tell the delivery boy what the prescription was and where to deliver it. He would converse with the customer, so that usually the prescription would come before the customer had hung up the phone. In 1909, he purchased one of the busiest pharmacies in Chicago with a partner,

Sex in the Media Essay -- Papers

Sex plays a major role in today's society. From television, radio, music, and advertisements, to video games, the Internet, art and pictures, all forms of media use sex to help sell their products. With the public being exposed to so many different types of media, the overuse of sex is common. Is sex a useful tool, or a ploy to get the attention of the public? Before discussing sex in the media, one must understand why it has come to be that people use sex as a gimmick. "The writing of modern history has resulted in a viewpoint that is nothing short of a stag party. The history of women is ignored, hushed up, and censored in the most literal sense of the term. This method of eliminating the social and political destiny of half of humanity is the most effective form of supremacy." (Janssen-Jurreit 189) The world as it exists today, is still man-made, no less now then in the nineteenth century. Alice E. Courtney states, "Women's self-awareness as females has until very recently reflected the world's (mostly men's) image of them; how well their personal performance matched male expectations." These individual roles, as described by Oneill and Leone in Male/Female Roles: Opposing Viewpoints as the relationship of a man or woman to society on the basis of gender, became essential in shaping male and female attitudes towards one another. Over the past twenty years remarkable changes in these traditional male and female roles have been witnessed. The subsequent impact on men, women, and families due to these changes is believed to be, by many social historians, caused by the re-emergence of the women's movement. (Oneill and Leone 138) Though a positive alteration of roles has occurred, how is it that childr... ...New York. Thousand Oaks. 1994 Davis, Simone Weil. "Living up to the Ads: Gender Fictions of the 1920s." Conn. Durham Dike Press. 2000 Dines, Gail and Jean M. Humez. "Gender, Race, and Class in Media: a Text Reader." California. Thousand Oaks. 1995 Goffman, Erving. Gender Advertisements. Boston: University Press. 1974 Holtzman, Linda. "Media Messages: What Film, Television, and Popular Music Teach us about Race, Sex, and Gender Roles." New York. Sharp. 2000 Impoco, Jim. (1996 April). Tv's frisky family values. U.S. News & World Report 120 no 15, p. 58-62. Janssen-Jurreit, Marie Louise. (1982). Sexism: The Male Monopoly on History & Thought. New York: Farrar Straus Giroux Oneill, M. Teresa, Leone, Bruno. (1983). Male/Female Roles: Opposing Viewpoints. St. Paul. Greenhaven Press.

Control System- Pressure Regulator

A type or certain group of elements that function together as a unified whole, is a system. This widened description thus gives some meaning to control systems as a whole. By re-establishing the basic principles and functions worked out, a system's limit can be extended to include little or more characteristics just as long as each singular variable contributes in a way to the particular system activity. This explains that the system does not halt interaction to other systems or peripherals. In the process industry, the term control system is sometimes normally used to specify a process, and the apparatus basically required to run the process. The system is tested with various actions so it will conform to a standard, these include; load, commands and disturbances which cause it to respond in some individual manner. A system is best made so that it will respond positively. In order for a system to act in the way prescribed is to control the system. The basic concept of comparing the measured and prescribed system performance, and then taking any action to change the process thereby minimizing errors, is called negative feedback. The system can vice-versa be called a closed-loop control system, or a negative feedback control system. To make a system automated it should be mechanized. To create the maintenance of a constant value in a control, is not the major primary objective of control; once the prescribed behavior is achieved, the control function is fulfilled. Although the use of control measure is in most cases involved with mechanical equipment, they can also be used in fields such as (e.g. in the social, biological or in different other systems). The science of achieving control, by using or not using feedback, is the method of control theory. This is applicable to system control in general. Most control systems have evolved by the practice of trial and error, for the critical design of system controls with the need for extensive analysis of two factors, the control devices and the process. 2.0 TYPES OF REGULATORS- 2.1 SIMPLE PRESSURE CONTROL SYSTEM (SELF OPERATED REGULATOR): For a typical uncontrolled system, let us say it is required for it to provide a standard pressure, P, at a given measure and that the discharge, Q2, provides for an external system, which, its need for this fluid varies. At a given time interval, the external system regulates valve No. 2 to comply with the needed specifications. The curves given in Fig 1.0 FIG 1.1 Shows the way in which it alters the process of the pressure. In earlier results in time, t1, some initial stable condition exists where, Q1 and Q 2 are of the same and the process pressure is significantly at the aimed equivalent. A level change occurs at, Q1 when time is at, t1, this reduces the fluid mass between the valves. This is followed mainly by a drop in the process pressure. For a system which is uncontrolled the pressure decline will continue until the drop over valve No. 1 is enough again to build equal flows and a new constant state functioning condition is gained. The procedure can be controlled; i.e. the suitable needed pressure can be managed if the significant rise in Q1 were gotten by increasing the opening of valve No. 1. A typical way of doing this is given in Fig 1.1. FIG 1.3 The response for the process pressure is sent to a spring opposed diaphragm that gives free way for the pressure to manoeuvre the valve. In a working mode, the contraction in the spring will be set so that at some constant state working condition the required process pressure, acting on the diaphragm section, this balances the force that the spring carries. The aimed process pressure is known as a set point. Changes from the set point which is caused by load variation will be controlled because as the process pressure differs, the matching force given back to the diaphragm will regulate the valve position to reduce the pressure variance to a certain range of value around the set point. The careful control of the pressure will rely on how big a flow change the regulator will be able to carry out for a minimal amount of pressure. The regulator flow change to process pressure change is the gain of the regulator and this will rely on the diaphragm area, the valve size, stiffness of the spring, and the general pressure drop over it. The corrective activity done by the regulator is proportional to the change of the process from its set point. Such an element is called the proportional or proportional mode, control. When using the proportional control, the corrective action can only carry on when some different outlines exist. The final pressure change needed to completely stroke the regulator is known as the proportional band and it shows around what limits the regulator can control. FIG 1.4 illustrates where the process measurement supplies the whole valve actuating force, this is known as self-operated regulators. FIG 1.5 The above demonstrates a self operated regulators made for the control of temperature, flow and level. The operation method is practically the same with the pressure regulator. They are widely used in various applications of specialty in the industrial field. 3.0 PILOT OPERATED PRESSURE REGULATOR: This regulator uses a little pilot valve assembly to aide in actuating the main valve. Generally the pilot operated pressure regulator shown in Fig 1.6 FIG 1.6 when in operation, the process pressure works on the lower side of the main diaphragm which is similar to the self operated regulator. The pilot also quantifies the process pressure and, upstream pressure as power source, changes the loading on the top side of the main diaphragm. The diaphragm serves as an amplifier, generally bearing a gain from process to loading pressure of 10 to 20 psi per psi. This is because of both feed back path ways one through the direct one and the other through the pilot, the regulators demonstrate a more complex control action than the simple proportional mode. The pilot operated regulator are available for all the four major process variables; flow, pressure level and temperature even though the direct acting path is left out in some cases. With the pilot operated regulator it is generally easier to achieve a greater regulator gain. Both the self and pilot operated regulators share similar attributes that have, in many cases, brought about some restraints. In some instances like if the fluid is corrosive, loaded with contaminants or of very high temperature, apparent issues may arise. Essentially at most one of the diaphragm casings, should, be able, to hold the maximum process pressure. The most possibly vital deficiency, from, the basis that static and dynamic elements of any specific form of process; i.e., level, pressure, etc. can differ respectively from one installation to the other so the choice of the amount of gain to be designed into a regulator without causing any sort of system instability, is made a very tasking procedure. It means that the regulator can not be altered to suit the characteristics of the process to which it has been applied. This Fig 1.7 is the block diagram of a pilot operated regulator FIG 1.7 3.1 INSTRUMENT CONTROL: The pressure control system illustrated in Fig 1.8 FIG 1.8 it surpasses all the limits considerably attached to the self and pilot operated regulators. It generally contains three detachable hardware pieces: the process controller, the control valve, and the valve actuator. Other controllers such as this stands for one of an entire family of peripherals generally referred to as instruments. The process fluid touches only the control valve and its sensing element. This is a small part which has no orifice and could get contaminated. They can be made from several types of materials to achieve high standard against corrosion and temperature. An external source for pneumatic power is used for working parts in the controller to provide clean, dry instrument air. The air supply is regulated so that the pressure is at a standard rate and that the controller and actuator are made to work with a standard pressure signal level, free of the process fluid pressure. A regular standard pressure supply is within 20 psig with a usual ranging of signal within 2 to 15 psig. They are ready for use with numerous sensing element and they give the significance of the process which is being controlled. They are commonly known as indicative controllers. To minimize trial and error the set point is normally calibrated to generally prevent subsequent start ups. The Fig 1.8 is like most pneumatic controller models, it has two levels with an adjustable measure of response and amplification around both levels. The input variable moves an end of a beam which holds the air flow through a nozzle. The pressure of the nozzle is sensitive to the point of the beam itself. The pressure of the nozzle performs on the top diaphragm of a pressure equal valve assembly that is the second amplifier level. As a result of the huge valve ports it is has the capacity to give an extreme flow progression to the actuator which works as a power amplifier. The pressure is given back to the amplifiers which moves the nozzle beams in a direction which opposes the sensing effect. Element motion ( i.e. negative feedback ). The three way valve behaves as a pressure divider and its regulation decides what amount of feedback should be consumed. Leaving the dynamics out, the controller can be seen as having a high gain movement path with a regulated gain response path. It provides only proportional control mode but its area of reach can be freely adjusted over a vast range by means of the pressure divider. The purpose of the integral mode is to remove any steady state process deviation and the reason for the deviation mode is to give an improved transient control. These modes improve the flexibility of the controller. 4.0 COMPUTER CONTROL- The reason for central control is to bring to a particular location, adequate information and hardware to allow an operator to control the plant variances, which are product yield and quality, and to manage the automated control of process variances, which are flow and temperature. In order for all duties to be carried out by the operator must have a sound knowledge of process variances, but how they should be. The adequate values for the process variances will differ as operating circumstances may be affected by things such as contamination, variations in reactants, load, changes in the products wanted or quality. The set points calculation can be made from the plant requirements and information about the plant operating elements. The early use of digital computers for process controls was for plant performance calculation the whole system works in an automated form sampling of transmitter signals. The optimizing of control and direct digital controls in Fig 1.9 FIG 1.9 Illustration of the hierarchy control as given in FIG 2.0 LLOYD, SHELSON, G AND ANDERSON, GERALD, D. 1971. Industrial Control Process. An Introduction to Hardware .1st edn. Marshaltown, Iowa: Fisher Controls Co. pp. 83-92. 5.0 CONTROL ELEMENTS- 5.1 BASIC ELEMENT: Any system can be broken down into various divisions for understanding it's rather important to consider two levels of dub divisions. The first are those components in a control loop that are manufactured, tested, purchased and even design as standalone pieces of equipments. 5.2 MATHEMATICAL MODELS OF PHYSICAL DEVICES: The mathematical representation of physical devices can be done with the use of the fundamental physical laws which include Ohm's Law Newton's Laws, flow equations, conservation of mass and energy, etc. The use of impedance is often but not always helpful when deriving a mathematical model when a system is dynamic there is a circumstance which is forcing the change. This force is always some kind of potential energy .When a change occurs that is the dynamic system which is a movement known as flux. This flux generally depends on the physical characteristics of the system. Some forms of flux are shown in Table 1.0. TABLE 1.0 Impedance shows the mathematical relationship between potential and flux, it is the ratio of an increase change in potential to an increase change in flux. EQUATION. 1 LLOYD, SHELSON, G AND ANDERSON, GERALD, D. 1971. Industrial Control Process. Basic Elements.1st edn. Marshaltown, Iowa: Fisher Controls Co. pp. 93-94. 6.0 PROCESS CONTROL SYSTEM The performance of a process control system is calculated by considering the system's output to the set point. The difference between both amounts is error or system deviation .The response of a regulatory system, for a step increase in load. Many standard words are defined in the schematic and several of them are used to describe the mistakes which might occur. It is obvious that no certain way such as settling time, maximum value of transient deviation, steady- state deviation gives a measure of system performance. Different approaches methods have been used for the error index. A tank which has several sources of flow as given in Fig 2.1 can be easily described by using block diagrams and flow components. For easy understanding lets say Pc = constant. The equation for flow is: PRESSURE PROCESS STEADY FLOW (FIG 2.1) In order to illustrate the nature of a process control system consider Fig 2.2 for the control equipment has a valve, diaphragm, actuator, and a locally mounted PI measuring controller FIG 2.2 LLOYD, SHELSON, G AND ANDERSON, GERALD, D. 1971. Industrial Control Process. Process Dynamics .1st edn. Marshaltown, Iowa: Fisher Controls Co. pp. 202-204. 7.0 ACCURACY AND SENSITIVITY 7.1 ACCURACY â€Å"In general, the greatest accuracy-closest regulation-is obtained with the largest diaphragm and shortest range which will give the required control pressure. For example, a control pressure of 40 psig can be obtained with any of the three ranges in model RP-1065-A and with two of the three ranges in model RP-1066-A. Closest regulation can be expected with the 5 – 50 psi range of model RP-1066-A (size 10 diaphragm). See table for â€Å"Accuracy of Regulation.† Unbalanced port areas are not considered in the values tabulated. Small amounts of unbalance are present in single-seated 1/2†³ â€Å"A† valves and in semi-balanced double seated valves 2†³ through 4†³. Under conditions of high pressure drop, the forces opposing valve closure will influence selection of the regulator model (diaphragm size). See â€Å"Accuracy of Regulation† tabulation for actual port area unbalance† FIG 2.3 [WWW] http://www.skilenvironmental.com/documents/160_RP1065A_1066A.pdf In addition what changes can made to the diaphragm area, spring rate, orifice size, and inlet pressure, the regulator accuracy can be enhanced by simply putting a pitot tube. Internal to the regulator, the pitot tube joins the diaphragm cover with a low-pressure, high velocity region inside the regulator body. The pressure in the area will be lower than P2 when it goes downstream. By using a pitot tube to calculate the lower pressure, the regulator change in its response to any change in P2. The pitot tube tricks the regulator. 7.2 SENSITIVITY The principle of operation and loading, actuating, and control components are in all designs. Many regulators use simple wire coil springs to control the downstream pressure. Numerous size springs are used to allow regulation of the secondary pressure around a target range. The needed pressure is at the centre one-third of the rated outlet pressure range. In the lower end of the pressure range, the spring loses some sensitivity; at the high end, the spring close to it maximum capacity. Regulators can use diaphragm or piston to detect or sense downstream pressure. Diaphragms are more sensitive to pressure variations and react quicker. They can operate where sensitive pressure settings are needed (lower than 0.04 psi). Pistons generally are more rugged and give a larger effective sensing area in a particular size regulator. The functional difference between general-purpose and precision regulators is the degree of control accuracy of the output pressure. Output pressure accuracy is gotten by the droop due to flow changes (regulator characteristics). [WWW] http://machinedesign.com/article/pneumatic-pressure-regulators-1115 8.0 FEEDBACK This section will develop the performance limitations imposed by a particular load when a conventional flow control valve is utilized in the valve-actuator component. It will then show that the load versus flow characteristic of the forward loop can be modified very advantageously. Various techniques utilized in the past for this purpose, such as controlled actuator by-pass leakage and structural feedback, are compared with a new technique called dynamic pressure feedback (D.P.F.). The analytical work is fortified by reports of actual tests of a representative system. The electrohydraulic position servo can be represented by the block diagram shown in Fig 2.4. This diagram separates the valve-actuator integration from the hydraulic and structural compliance of the actuator. The diagram also represents the particular load case under discussion. The analysis of servo stability and performance is affected by the choice of position feedback location. Output position can be measured at the actuator or at the load. If the feedback is from the actuator position, the analytical task is made more difficult. However, it is apparent from the block diagram that the quantities Xp and X0 react in a proportional manner to inertia forces. It is reasonable to conclude, therefore, that the two cases should yield similar results. This discussion will be based on selection of feedback intelligence from the load position, X0, due to the relative simplicity of analysis. However, a careful comparison of this simpler case with the more difficult to analyse case of actuator feedback position has been carried out. An analogue computer was utilized for this comparison. The results of the study confirmed that the two cases are really very similar in dynamic performance achievable. The use of actuator position feedback suffers some comparative penalty statically with respect to error introduced by external (load disturbance) forces.† [WWW] http://www.emeraldinsight.com/Insight/ViewContentServlet;jsessionid=6464D27CC3E73FAFE7C6220F352B4F85?contentType=Article&Filename=/published/emeraldfulltextarticle/pdf/1270320604.pdf FIG 2.4 [WWW]http://www.emeraldinsight.com/Insight/ViewContentServlet;jsessionid=6464D27CC3E73FAFE7C6220F352B4F85?contentType=Article&Filename=/published/emeraldfulltextarticle/pdf/1270320604.pdf 9.0 PRESSURE MEASUREMENT â€Å"Fluid pressure can be defined as the measure of force per-unit-area exerted by a fluid, acting perpendicularly to any surface it contacts (a fluid can be either a gas or a liquid, fluid and liquid are not synonymous). The standard SI unit for pressure measurement is the Pascal (Pa) which is equivalent to one Newton per square meter (N/m2) or the KiloPascal (kPa) where 1 kPa = 1000 Pa. In the English system, pressure is usually expressed in pounds per square inch (psi). Pressure can be expressed in many different units including in terms of a height of a column of liquid. CONVERSION UNITS FOR COMMON UNITS OF PRESSURE (TABLE 2) PRESSURE TERMS RELATIONSHIP (FIG 2.5) Table lists commonly used units of pressure measurement and the conversion between the units. Pressure measurements can be divided into three different categories: absolute pressure, gage pressure and differential pressure. Absolute pressure refers to the absolute value of the force per-unit-area exerted on a surface by a fluid. Therefore the absolute pressure is the difference between the pressure at a given point in a fluid and the absolute zero of pressure or a perfect vacuum. Gage pressure is the measurement of the difference between the absolute pressure and the local atmospheric pressure. Local atmospheric pressure can vary depending on ambient temperature, altitude and local weather conditions. The U.S. standard atmospheric pressure at sea level and 59à ¯Ã‚ ¿Ã‚ ½F (20à ¯Ã‚ ¿Ã‚ ½C) is 14.696 pounds per square inch absolute (psia) or 101.325 kPa absolute (abs). When referring to pressure measurement, it is critical to specify what reference the pressure is related to. In the English system of units, measurement relating the pressure to a reference is accomplished by specifying pressure in terms of pounds per square inch absolute (psia) or pounds per square inch gage (psig). For other units of measure it is important to specify gage or absolute. The abbreviation .abs' refers to an absolute measurement. A gage pressure by convention is always positive. A .negative' gage pressure is defined as vacuum. Vacuum is the measurement of the amount by which the local atmospheric pressure exceeds the absolute pressure. A perfect vacuum is zero absolute pressure. Fig 2.5 shows the relationship between absolute, gage pressure and vacuum. Differential pressure is simply the measurement of one unknown pressure with reference to another unknown pressure. The pressure measured is the difference between the two unknown pressures. This type of pressure measurement is commonly used to measure the pressure drop in a fluid system. Since a differential pressure is a measure of one pressure referenced to another, it is not necessary to specify a pressure reference. For the English system of units this could simply be psi and for the SI system it could be kPa. In addition to the three types of pressure measurement, there are different types of fluid systems and fluid pressures. There are two types of fluid systems; static systems and dynamic systems. As the names imply, a static system is one in which the fluid is at rest and a dynamic system is on in which the fluid is moving†. [WWW] http://www.scribd.com/doc/2339144/Understanding-Pressure-and-Pressure-Measurement 10.0 CONTROLLERS The major use of controllers is to detect errors in the variables and to create error correction messages that which is caused by the error. To complete this task the controller design must have an adjustable set point that can be comparison to the process variable. The error that is given is sent as a response for needed action to be carried out. The block diagram is given in Fig . The input could be as an input from the transmitter, which happens in the situation involving a receiver-controller. A three mode controller transfer function likely should be as given in the equation , the static gain has been resolved in two perspectives ; K is the nominal output and input spans and this would normally n=be unity for a receiver controller, and Kc is an adjustable measurement known as proportional gain. EQUATION. 2 The three modes stated above give the derivative, integral, and proportional modes respectively. FIG 2.6 Simpler controller designs employing one or two modes are often used. The basic combinations are P- Proportional only I- Integral only PI- proportional plus integral PD proportional plus derivative PID proportional plus integral plus derivative The transfer function may be derived from EQUATION. 2 by eliminating the appropriate terms. In the self operated regulator the actuator, controller and sensor are normally the same thing and with the same element. The controller has no other than the set point and has fixed gain and practically no adjustments. The transfer function is taken as: EQUATION. 3 Considering an example with a regulator with a set point of 5 psig and a flow capacity of 0.6, a temperature of 60 degree (Fahrenheit) and a pressure of 5 psig. The off set flow capacity will be 20 percent. The density can be determined with the use of the equation of state of a perfect gas as shown below: CALCULATION .1 LLOYD, SHELSON, G AND ANDERSON, GERALD, D. 1971. Industrial Control Process. Control Components .1st edn. Marshaltown, Iowa: Fisher Controls Co. pp. 115 – 148. 11.0 INPUT AND OUTPUT â€Å"This simple valve model has three states: OPEN, WORKING, and CLOSED. As the valve is the only component of the pressure-regulator that has state, the composite device, likewise, has only three states: [OPEN], [WORKING], and [CLOSED]. Suppose the input pressure is decreasing and the pressure-regulator is in state [WORKING], then dXFp = +, which causes A, the cross-sectional area available for flow to increase. This raises the possibility that A